Symbol
Name
ID

Fbxo7
F-box protein 7
MGI:1917004

Phenotype annotations related to hematopoietic system

*	Aspects of the system are reported to show a normal phenotype.
	Darker colors indicate more annotations

Mouse Phenotypes

hematopoietic system phenotype

thymus atrophy

thymus hypoplasia

enlarged spleen

increased spleen weight

increased pro-B cell number

abnormal T cell differentiation

increased double-negative T cell number

extramedullary hematopoiesis

anemia

hyperchromic macrocytic anemia

increased erythroid progenitor cell number

abnormal proerythroblast morphology

decreased erythroblast number

increased erythroblast number

decreased erythrocyte cell number

decreased hematocrit

decreased hemoglobin content

increased mean corpuscular hemoglobin

increased mean corpuscular hemoglobin concentration

increased mean corpuscular volume

increased red blood cell distribution width

anisocytosis

thrombocytosis

increased effector memory CD4-positive, alpha-beta T cell number

decreased CD4-positive, alpha-beta T cell number

increased effector memory CD8-positive, alpha-beta T cell number

decreased CD8-positive, alpha-beta T cell number

abnormal effector T cell number

increased memory T cell number

decreased T cell number

increased activated T cell number

decreased leukocyte cell number

abnormal reticulocyte cell number

reticulocytosis

increased erythrocyte clearance

Availability

Mouse Genotype

Fbxo7^{tm1a(EUCOMM)Hmgu}/Fbxo7^{tm1a(EUCOMM)Hmgu}

Fbxo7^{tm1a(EUCOMM)Wtsi}/Fbxo7^{tm1a(EUCOMM)Wtsi}

Fbxo7^{tm1c(EUCOMM)Wtsi}/Fbxo7^{tm1c(EUCOMM)Wtsi}
Tg(Cd4-cre)1Cwi/0 (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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